Pemphigus foliaceus with prominent neutrophilic pustules.

Authors :: Matsuo, K.
Komai, A.
Ishii, K.
Futei, Y.
Amagai, M.
Deguchi, H.
Danno, K.
Hashimoto, T.
Source :: British Journal of Dermatology. Jul2001, Vol. 145 Issue 1, p132-136. 5p.
Publication Year :: 2001
Abstract: We describe four patients with generalized scaly and pustular skin lesions showing extensive neutrophilic infiltration in the subcorneal region of the epidermis. Immunofluorescence, immunoblot and enzyme-linked immunosorbent assay analyses detected IgG antibodies reacting exclusively with desmoglein 1, the pemphigus foliaceus antigen. This study indicates that pemphigus foliaceus may show prominent neutrophilic pustular skin lesions. [ABSTRACT FROM AUTHOR]