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Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: Direct correlation...
- Source :
-
Proceedings of the National Academy of Sciences of the United States of America . 05/08/2001, Vol. 98 Issue 10, p5804. 5p. 4 Color Photographs, 6 Diagrams, 1 Graph. - Publication Year :
- 2001
-
Abstract
- Demonstrates that lack of insulin-like growth factor I (IGF-I) in knockout mice prevents normal retinal vascular growth, despite the presence of vascular endothelial growth factor. Comparison with studies in premature infants; Blinding disease retinopathy of prematurity caused by IGF-I insufficiency.
- Subjects :
- *SOMATOMEDIN
*RETROLENTAL fibroplasia
*PREMATURE infant diseases
Subjects
Details
- Language :
- English
- ISSN :
- 00278424
- Volume :
- 98
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Academic Journal
- Accession number :
- 4857384
- Full Text :
- https://doi.org/10.1073/pnas.101113998