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A new naphtho- γ-pyrone from mangrove endophytic fungus ZSU-H26.
- Source :
-
Chemistry of Natural Compounds . Mar2010, Vol. 46 Issue 1, p15-18. 4p. 1 Chart. - Publication Year :
- 2010
-
Abstract
- A new naphtho- γ-pyrone, 5-hydroxy-6,8-dimethoxy-2-benzyl-4H-naphtho[2,3-b]-pyran-4-one ( 1), together with three known compounds 5,7-dihydroxy-2-methylbenzopyran-4-one ( 2), 3,5-dihydroxy-2,7dimethylbenzopyran-4-one ( 3) and cyclo(Tyr-Tyr) ( 4) were isolated from the mangrove endophytic fungus Phomopsis sp. ZSU-H26 obtained from the South China Sea. Their structures were elucidated by spectroscopic methods, mainly 1D and 2D NMR spectroscopic techniques. Primary bioassays showed that 1 exhibited cytotoxicity against HEp-2 and HepG2 cells with IC50 values of 10 and 8 μg/mL, respectively. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NAPHTHOQUINONE
*NAPHTHALENE
*ENDOPHYTIC fungi
*MANGROVE plants
Subjects
Details
- Language :
- English
- ISSN :
- 00093130
- Volume :
- 46
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Chemistry of Natural Compounds
- Publication Type :
- Academic Journal
- Accession number :
- 49086993
- Full Text :
- https://doi.org/10.1007/s10600-010-9514-8