Back to Search Start Over

P19ARF targets certain E2F species for degradation.

Authors :
Martelli, Fabio
Hamilton, Timothy
Silver, Daniel P.
Sharpless, Norman E.
Bardeesy, Nabeel
Rokas, Mikhail
DePinho, Ronald A.
Livingston, David M.
Grossman, Steven R.
Source :
Proceedings of the National Academy of Sciences of the United States of America. 04/10/2001, Vol. 98 Issue 8, p4455. 6p. 13 Color Photographs, 14 Graphs.
Publication Year :
2001

Abstract

Investigates the effects of alternative reading frame protein p19ARF on the abundance of E2F transcription factor family in cells. Destabiization of E2F1; Reduction in the endogenos stability E2F1 and E2F3; Association of p19ARF with E2F1, E2F2 and E2F3.

Details

Language :
English
ISSN :
00278424
Volume :
98
Issue :
8
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
4961031
Full Text :
https://doi.org/10.1073/pnas.081061398