A Pneumococcal Capsular Polysaccharide Vaccine Induces a Repertoire Shift with Increased VH 3 Expression in Peripheral B Cells from Human Immunodeficiency Virus (HIV)-Uninfected but Not HIV-Infected Persons.

Examines the influence of pneumococcal vaccination on the V[sub H] gene subgroup expression of HIV and non-HIV patients in the United States. Application of polymerase chain reaction enzyme-linked immunosorbent assay; Acceleration of polysaccharide antibodies; Amplification of V[sub H] genes.