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Peritoneal dialysis-associated peritonitis: clinical features and predictors of outcome
- Source :
-
International Journal of Infectious Diseases . Jun2010, Vol. 14 Issue 6, pe489-e493. 0p. - Publication Year :
- 2010
-
Abstract
- Abstract: Objectives: The objective of this study was to identify the epidemiological, clinical, and microbiological factors affecting the outcome of peritoneal dialysis (PD)-associated peritonitis. Methods: All patients with PD-associated peritonitis, cared for at the University Hospital of Heraklion from 1990 to 2007, were retrospectively studied. Results: A total of 247 episodes of PD-associated peritonitis occurring in 82 patients were evaluated. The median age of patients was 68 years (range 10–92 years); 51 (62%) were males. There were 104 episodes (42%) of Gram-positive peritonitis, 46 (19%) of Gram-negative peritonitis, 13 (5%) of polymicrobial peritonitis, and 11 (4%) of fungal peritonitis. There were 64 (26%) complicated episodes. The latter included 22 (8.9%) relapses, 13 (5.3%) repeated episodes, 18 (7.3%) catheter removals, and 11 (4.5%) deaths. In multivariate analysis, the presence of a purulent exit-site infection (p <0.001), peritoneal dialysis effluent cell count >100×106/l for more than 5 days (p <0.001), use of antimicrobials during the preceding 3 months (p <0.05), and low serum total protein level on admission (p <0.05) were independent predictors of a complicated course. Conclusions: Exit-site infection, more than 5 days with a peritoneal dialysis effluent cell count >100×106/l, prior use of antimicrobials, and low serum total protein level are potential predictors of complicated PD-associated peritonitis and may distinguish high-risk cases. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 12019712
- Volume :
- 14
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- International Journal of Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 50707194
- Full Text :
- https://doi.org/10.1016/j.ijid.2009.07.016