Device therapy in patients with heart failure and preserved ejection fraction (HFPEF): a new frontier?

The author reflects on the use of cardiac resynchronization therapy (CRT) in heart failure patients with preserved ejection fraction (HFPEF). The author relates on two studies published within the issue such as one on the use of CRT in patients with left ventricular ejection fraction (LVEF) and the other on CRT use for casual treatment of HFPEF. The author calls for further mechanistic studies regarding CRT use for HFPEF with short diastolic filling times and /or diastolic dyssynchrony.