Back to Search
Start Over
A comparison of the effect on QT interval between thiamylal and propofol during anaesthetic induction.
- Source :
-
Anaesthesia . Jul2010, Vol. 65 Issue 7, p679-683. 5p. 3 Charts, 1 Graph. - Publication Year :
- 2010
-
Abstract
- The aim of this study was to determine the effect of thiamylal and propofol on heart rate-corrected QT (QTc) interval during anaesthetic induction. We studied 50 patients undergoing lumbar spine surgery. Patients were administered 3 μg.kg−1 fentanyl and were randomly allocated to receive 5 mg.kg−1 thiamylal or 1.5 mg.kg−1 propofol as an induction agent. Tracheal intubation was performed after vecuronium administration. Heart rate, mean arterial pressure, bispectral index score, and 12-lead electrocardiogram were recorded at the following time points: just before (T1) and 2 min after (T2) fentanyl administration; 2 min after anaesthetic administration (T3); 2.5 min after vecuronium injection (T4); and 2 min after intubation (T5). Thiamylal prolonged (p < 0.0001), but propofol shortened (p < 0.0001), the QTc interval. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HEART beat
*INTUBATION
*SPINAL surgery
*ELECTROCARDIOGRAPHY
*FENTANYL
Subjects
Details
- Language :
- English
- ISSN :
- 00032409
- Volume :
- 65
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Anaesthesia
- Publication Type :
- Academic Journal
- Accession number :
- 51325089
- Full Text :
- https://doi.org/10.1111/j.1365-2044.2010.06341.x