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The Role of Tyr248 Probed by Mutant Bovine Carboxypeptidase A: Insight into the Catalytic....

Authors :
Jae Hyun Cho
Kim, Dong H.
Do-Hyung Kim
Kyung Joo Lee
Kwan Yong Choi
Source :
Biochemistry. 8/28/2001, Vol. 40 Issue 34, p10197. 7p. 1 Black and White Photograph, 3 Diagrams, 2 Charts, 3 Graphs.
Publication Year :
2001

Abstract

Investigates the role of Tyr248 in the catalysis of carboxypeptidase A (CPA). Removal of C-terminal amino acid residue by CPA; Use of CPA in the development of inhibitor design strategies; Importance of Tyr248 in the hydrolysis of enzymes.

Subjects

Subjects :
*CATALYSIS
*CARBOXYPEPTIDASES

Details

Language :
English
ISSN :
00062960
Volume :
40
Issue :
34
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
5192026
Full Text :
https://doi.org/10.1021/bi010807j