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Germinal center-associated nuclear protein (GANP) has a phosphorylation-dependent DNA-primase....

Authors :
Kuwahara, Kazuhiko
Tomiyasu, Shinjirou
Fujimura, Satoru
Nomura, Kazumi
Yan Xing
Nishiyama, Noriko
Ogawa, Michio
Imajoh-Ohmi, Shinobu
Izuta, Shunji
Sakaguchi, Nobuo
Source :
Proceedings of the National Academy of Sciences of the United States of America. 8/28/2001, Vol. 98 Issue 18, p10279. 5p. 2 Color Photographs, 1 Black and White Photograph, 1 Diagram, 2 Graphs.
Publication Year :
2001

Abstract

Reports the involvement of DNA-primase germinal center-associated nuclear protein (GANP) in regulation of cell proliferation of antigen-driven B cells in germinal centers. Effect of over expressed GANP in cell cycling; Need of GANP DNA-primase activity in organs with extraordinary rapid cell proliferation; Phosphorylation of GANP DNA-primase.

Subjects

Subjects :
*DNA
*GERMINAL centers
*B cells

Details

Language :
English
ISSN :
00278424
Volume :
98
Issue :
18
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
5192374
Full Text :
https://doi.org/10.1073/pnas.181335698