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A new xanthone derivative from mangrove endophytic fungus No. ZSU-H16.
- Source :
-
Chemistry of Natural Compounds . Jul2010, Vol. 46 Issue 3, p348-351. 4p. 1 Chart. - Publication Year :
- 2010
-
Abstract
- A new xanthone derivative, 3,5,8-trihydroxy-2,2-dimethyl-3,4,4-trihydro-2 H,6 H-pyrano[3,2- b]-xanthen-6one ( 1), together with three known compounds, 5,8-dihydroxy-2,2-dimethyl-2 H,6 H-pyrano[3,2- b]xanthen6-one ( 2), cyclo-( N- O-methyl-L-Trp-L-Ile-D-Pip-L-2-amino-8-oxo-decanoyl) ( 3), and cyclo-(Phe-Tyr) ( 4), was isolated from the mangrove endophytic fungus No. ZSU-H16 obtained from the South China Sea coast. Their structures were elucidated by spectroscopic methods, mainly 1D and 2D NMR spectroscopic techniques. Compound 1 exhibited cytotoxicity against KB and KBV 200 cells with IC50 values greater than 50 μg/mL, respectively. [ABSTRACT FROM AUTHOR]
- Subjects :
- *XANTHONE
*ENDOPHYTIC fungi
*MANGROVE plants
*METABOLITES
*BIOACTIVE compounds
Subjects
Details
- Language :
- English
- ISSN :
- 00093130
- Volume :
- 46
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Chemistry of Natural Compounds
- Publication Type :
- Academic Journal
- Accession number :
- 52191345
- Full Text :
- https://doi.org/10.1007/s10600-010-9614-5