Diastereoselective approach to novel octahydroisoquinolones and an extension to its one-pot synthesis

Authors :: Singh, Pardeep
Bhargava, Gaurav
Kumar, Vipan
Mahajan, Mohinder P.
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Aug2010, Vol. 51 Issue 32, p4272-4274. 3p.
Publication Year :: 2010
Abstract: Abstract: The present Letter describes the use of β-lactams for the synthesis of functionalized β-amino esters and their transformation to trisubstituted octahydroisoquinolone derivatives in good yields with an extension to their one-pot synthesis. [Copyright &y& Elsevier]

Subjects :: *STEREOCHEMISTRY
*HETEROCYCLIC compounds
*ORGANIC synthesis
*ESTERS
*SUBSTITUTION reactions
*LACTAMS

Language :: English
ISSN :: 00404039
Volume :: 51
Issue :: 32
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 52200900
Full Text :: https://doi.org/10.1016/j.tetlet.2010.06.038

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