Genome-wide analysis of DNA turnover and gene expression in stationary-phase Saccharomyces cerevisiae.

The article presents a study on a genome-wide DNA synthesis activity in stationary-phase Saccharomyces cerevisia. It states that stationary-phase cultures of a haploid strain was used to detect and characterize the DNA synthesis and turnover in yeast's stationary-phase cultures which can efficiently incorporate very small concentrations of external 5-bromo-2-deoxyuridine (BrdU) into its DNA. Results show that during the stationary-phase in yeast, a genome-wide of DNA synthesis occurs.