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Episodic Memory in Dementia: Characteristics of New Learning that Differentiate Alzheimer's, Huntington's, and Parkinson's Diseases.
- Source :
-
Archives of Clinical Neuropsychology . Aug2010, Vol. 25 Issue 5, p396-409. 14p. 6 Charts, 2 Graphs. - Publication Year :
- 2010
-
Abstract
- Differences in the memory characteristics of patients with Alzheimer's disease (AD), Huntington's disease (HD), and Parkinson's disease (PD) were investigated with tests that assess learning and retention of words, line-drawn objects, and locations. Large groups of AD, HD, and PD patients were administered the Hopkins Verbal Learning Test-Revised (HVLT-R) and the Hopkins Board (HB). Eight learning and memory measures were subjected to discriminant function analysis. A 91% classification accuracy was achieved for the separation of cortical and subcortical dementias and 79% accuracy for the discrimination of the three groups. The delayed recall of items was the best discriminator. Receiver-operating curve analysis indicated up to 90% sensitivity and 90% specificity in differentiating the three diseases using the discriminant scores. Individual learning and memory measures of the HVLT-R and the HB provided very high sensitivity and specificity in distinguishing cortical versus subcortical dementias and modest accuracy in separating the two subcortical diseases. [ABSTRACT FROM PUBLISHER]
Details
- Language :
- English
- ISSN :
- 08876177
- Volume :
- 25
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Archives of Clinical Neuropsychology
- Publication Type :
- Academic Journal
- Accession number :
- 52348189
- Full Text :
- https://doi.org/10.1093/arclin/acq038