Postexposure Treatment of Marburg Virus Infection.

Authors :: Geisbert, Thomas W.
Hensley, Lisa E.
Geisbert, Joan B.
Leung, Anders
Johnson, Joshua C.
Grolla, Allen
Feldmann, Heinz
Source :: Emerging Infectious Diseases. Jul2010, Vol. 16 Issue 7, p1119-1122. 4p. 2 Charts, 1 Graph.
Publication Year :: 2010
Abstract: Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus-based vaccine is administered 20-30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection. [ABSTRACT FROM AUTHOR]