Axially chiral C 2-symmetric N-heterocyclic carbene (NHC) palladium complexes-catalyzed asymmetric arylation of aldehydes with arylboronic acids

Abstract: Chiral C 2-symmetric N-heterocyclic carbene (NHC) palladium diaquo complexes 5a–c and the chiral C 2-symmetric NHC-palladium complexes 5d and 5e prepared from (R)-BINAM or H8-(R)-BINAM could be used as the catalysts for the enantioselective arylation of arylaldehydes with arylboronic acids in which NHC-Pd complex 5a was found to be fairly effective in this reaction to give the corresponding adducts in moderate enantioselectivities along with moderate to good yields. [ABSTRACT FROM AUTHOR]