REACŢIILE ADVERSE ALE TRATAMENTULUI HEPATITEI CRONICE VIRALE C.

Chronic viral hepatitis (VCH) is one of the most common chronic diseases. Main transmission ways are represented by blood and blood products. The standard therapy is based on the combination of alpha-pegylated interferon (PEG-IFN) plus ribavirin (RBV). The efficiency of this therapy was proved by several trials. Unfortunately, the PEG-IFN plus RBV therapy implies several side effects requiring a rigorous follow-up of the patients. Most common side effects are: pseudoflu, hematological, psychical, neurological, autoimmune thyroiditis etc. Other encountered side effects are alopecia, insomnia, sight and hearing troubles, anorexia, interstitial pneumonia, pancreatitis, inflammatory intestinal diseases, psoriasis. The management of side effects supposes periodical evaluation of the patients; when side effects occur, an efficient strategy is necessary to fight these side effects. [ABSTRACT FROM AUTHOR]