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Visualization of single RNA transcripts in situ .

Authors :
Femino, Andrea M.
Fay, Fredric S.
Fogarty, Kevin
Singer, Robert H.
Source :
Science. 4/24/1998, Vol. 280 Issue 5363, p585-590. 6p. 18 Color Photographs, 6 Black and White Photographs, 1 Diagram, 5 Graphs.
Publication Year :
1998

Abstract

Reports on experiments in which fluorescence in situ hybridization (FISH) and digital imaging microscopy were modified to allow detection of single RNA molecules. Use of synthesized oligodeoxynucleotide probes; Detection of RNA transcription; Implications of findings.

Details

Language :
English
ISSN :
00368075
Volume :
280
Issue :
5363
Database :
Academic Search Index
Journal :
Science
Publication Type :
Academic Journal
Accession number :
544481
Full Text :
https://doi.org/10.1126/science.280.5363.585