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Human cleavage-stage embryo vitrification is comparable to slow-rate cryopreservation in cycles of assisted reproduction.
- Source :
-
Journal of Assisted Reproduction & Genetics . Sep2010, Vol. 27 Issue 9/10, p549-554. 6p. - Publication Year :
- 2010
-
Abstract
- Objectives: To compare embryo survival, pregnancy and implantation rates after cryopreservation of human cleavage-stage embryos with slow-rate cryopreservation or vitrification. Study design: 262 patients, attending for assisted reproduction, were prepared for oocyte retrieval using standard controlled ovarian hyperstimulation protocols. Excess embryos were cryopreserved on day 3 either by vitrification, or slow-rate cryopreservation in a programmable freezer. Cycles of thawing were monitored for thaw efficiency, pregnancy and implantation rates. Results: Clinical pregnancy and implantation rates were highly comparable between cycles in which day 3 embryos were thawed either after slow-rate cryopreservation or vitrification. Conclusions: These data suggest that vitrification of human embryos during assisted reproduction cycles achieves comparable success rates to fresh cycles and therefore can be applied in the laboratory of assisted reproduction. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10580468
- Volume :
- 27
- Issue :
- 9/10
- Database :
- Academic Search Index
- Journal :
- Journal of Assisted Reproduction & Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 54632576
- Full Text :
- https://doi.org/10.1007/s10815-010-9452-1