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A preliminary evaluation of the validity of at-risk criteria for bipolar disorders in help-seeking adolescents and young adults
- Source :
-
Journal of Affective Disorders . Dec2010, Vol. 127 Issue 1-3, p316-320. 5p. - Publication Year :
- 2010
-
Abstract
- Abstract: Introduction: We have developed ultra-high risk criteria for bipolar affective disorder (bipolar at-risk — BAR) which include general criteria such as being in the peak age range of the onset of the disorder and a combination of specific criteria including sub-threshold mania, depressive symptoms, cyclothymic features and genetic risk. In the current study, the predictive validity of these criteria were tested in help-seeking adolescents and young adults. Method: This medical file-audit study was conducted at ORYGEN Youth Health (OYH), a public mental health program for young people aged between 15 and 24years and living in metropolitan Melbourne, Australia. BAR criteria were applied to the intake assessments of all non-psychotic patients who were being treated in OYH on 31 January, 2008. All entries were then checked for conversion criteria. Hypomania/mania related additions or alterations to existing treatments or initiation of new treatment by the treating psychiatrist served as conversion criteria to mania. Results: The BAR criteria were applied to 173 intake assessments. Of these, 22 patients (12.7%) met BAR criteria. The follow-up period of the sample was 265.5days on average (SD 214.7). There were significantly more cases in the BAR group (22.7%, n =5) than in the non-BAR group (0.7%, n =1) who met conversion criteria (p <.001). Conclusions: These findings support the notion that people who develop a first episode of mania can be identified during the prodromal phase. The proposed criteria need further evaluation in prospective clinical trials. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 01650327
- Volume :
- 127
- Issue :
- 1-3
- Database :
- Academic Search Index
- Journal :
- Journal of Affective Disorders
- Publication Type :
- Academic Journal
- Accession number :
- 55056610
- Full Text :
- https://doi.org/10.1016/j.jad.2010.06.016