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Keyhole and zero-padding approaches for reduced-encoding diffusion tensor imaging of the mouse brains
- Source :
-
Magnetic Resonance Imaging (0730725X) . Dec2010, Vol. 28 Issue 10, p1413-1419. 7p. - Publication Year :
- 2010
-
Abstract
- Abstract: Keyhole diffusion tensor imaging (keyhole DTI) was previously proposed in cardiac imaging to reconstruct DTI maps from the reduced phase-encoding images. To evaluate the feasibility of keyhole DTI in brain imaging, keyhole and zero-padding DTI algorithms were employed on in vivo mouse brain. The reduced phase-encoding portion, also termed as the sharing rate, was varied from 50% to 90% of the full k-space. Our data showed that zero-padding DTI resulted in decreased fractional anisotropy (FA) and decreased mean apparent diffusion coefficient (mean ADC) in white matter (WM) regions. Keyhole DTI showed a better edge preservation on mean ADC maps but not on FA maps as compared to the zero-padding DTI. When increasing the sharing rate in keyhole approach, an underestimation of FA and an over- or underestimation of mean ADC were measured in WM depending on the selected reference image. The inconsistency of keyhole DTI may add a challenge for the wide use of this modality. However, with a carefully selected directive diffusion-weighted image to serve as the reference image in the keyhole approach, this study demonstrated that one may obtain DTI indices of reduced-encoding images with high consistency to those derived with full k-space DTI. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0730725X
- Volume :
- 28
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Magnetic Resonance Imaging (0730725X)
- Publication Type :
- Academic Journal
- Accession number :
- 55334403
- Full Text :
- https://doi.org/10.1016/j.mri.2010.07.016