Artesunate versus quinine in the treatment of severe fakiparum malaria in African children (AQUAMAT): an open-label, randomised trial.

The article discusses a study which compared the effectiveness of parenteral treatment with either artesunate or quinine in African children with severe falciparum malaria. The open-label, randomised trial was conducted in 11 centres and involved children less than 15 years of age. The authors found that there was an association between artesunate and reduction in mortality in African children with severe malaria.