Back to Search
Start Over
Viewpoint: High susceptibility to Chikungunya virus of Aedes aegypti from the French West Indies and French Guiana.
- Source :
-
Tropical Medicine & International Health . Jan2011, Vol. 16 Issue 1, p134-139. 6p. - Publication Year :
- 2011
-
Abstract
- To estimate the vector competence of Aedes aegypti populations sampled from distinct anthropogenic environments in French Guiana, Guadeloupe and Martinique for the strain CHIKV 06.21. F/F females were orally infected at titres of 10 and 10 pfu/ml in blood-meals. Disseminated infection rates (DIR) of mosquitoes were estimated using indirect fluorescent antibody assay on heads' squashes, 7 or 14 days post-infection (pi). At a titre of 10 pfu/ml, DIR ranged from 88.9% to 100.0% and were not significantly different whether assessed at day 7 or 14 pi. At a titre of 10 pfu/ml, DIR observed 7 days pi ranged from 37.6 to 62.0%. Ae. aegypti from French Guiana and French West Indies are highly competent to transmit CHIKV. An evaluation of DIR 7 days rather than 14 days pi is adequate to estimate vector competence. The titre of 10 pfu/ml allows us to distinguish Ae. aegypti populations originating from distinct environments (dense or diffuse housing) by their vector competence. This assessment is a prerequisite to better evaluate the potential risk of Chikungunya outbreaks once the virus is introduced from endemic regions. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13602276
- Volume :
- 16
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Tropical Medicine & International Health
- Publication Type :
- Academic Journal
- Accession number :
- 55831669
- Full Text :
- https://doi.org/10.1111/j.1365-3156.2010.02613.x