Oxidation of 1-benzyldihydroisoquinolines or 1-benzyltetrahydroisoquinolines with dioxygen to 1-benzoylisoquinolines

Authors :: Gan, Haifeng
Lu, Yunyu
Huang, Yue
Ni, Lijun
Xu, Jinyi
Yao, Hequan
Wu, Xiaoming
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Mar2011, Vol. 52 Issue 12, p1320-1324. 5p.
Publication Year :: 2011
Abstract: Abstract: An environmental-benign methodology to synthesize 1-benzoylisoquinolines from 1-benzyl-3, 4-dihydroisoquinolines or 1-benzyl-1,2,3,4-tetrahydroisoquinolines using dioxygen as an oxidant was developed. This methodology in combination with Bischler-Napieralski reaction leads to a facile synthesis of 1-benzoylisoquinolines from phenylacetic acids and phenylethanamines. [Copyright &y& Elsevier]

Subjects :: *OXIDATION
*QUINOLINE
*OXYGEN
*ORGANIC synthesis
*CHEMICAL reactions
*AMINES
*PHENYLACETIC acid

Language :: English
ISSN :: 00404039
Volume :: 52
Issue :: 12
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 58538872
Full Text :: https://doi.org/10.1016/j.tetlet.2011.01.058

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