Update on Estrogen and Progesterone as Treatments of Mood Disorders in Women.

The article provides information on the biological effects of estrogen and progesterone and their use to treat mood disorders in women. It states that both hormones have neurotrophic properties that regulate cortical blood flow and affects the central nervous system. It discusses the use of progestin and transdermal 17ß-estradiol in hormone replacement therapy and combined oral contraceptives as treatment for premenstrual dysphoric disorder, unipolar depression, bipolar disorder and mood disorders in perimenopause and postmenopause.