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High Enantioselectivity and Broad Substrate Specificity of a Carbonyl Reductase: Toward...

Authors :
Ema, Tadahi
Moriya, Hiroyuki
Kofukuda, Toru
Ishida, Tomomasa
Maehara, Kentaro
Utaka, Masanori
Sakai, Takashi
Source :
Journal of Organic Chemistry. 12/14/2001, Vol. 66 Issue 25, p8682. 3p. 1 Chart.
Publication Year :
2001

Abstract

Reports on the high enantioselectivity and broad substrate specificity of a carbonyl reductase. Overview on the procedure for the purification of the enzyme and asymmetric reductions; Obtaining optically active alcohols useful for organic synthesis by the enzymatic reductions; Transformation of aliphatic and aromatic ketones; Stereochemical trend in the enzymatic reductions.

Details

Language :
English
ISSN :
00223263
Volume :
66
Issue :
25
Database :
Academic Search Index
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
5941324
Full Text :
https://doi.org/10.1021/jo0108257