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Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates.
- Source :
-
Chemical Reviews . Feb2011, Vol. 111 Issue 2, p455-529. 75p. 132 Diagrams, 107 Charts. - Publication Year :
- 2011
-
Abstract
- The article talks about enantiopure trifluoromethylated molecules. Fluorine has been one of the elements that played a critical role in the pharmaceutical and material sciences. The addition of one or two flourine atoms has been a familiar technique in every new drug discovery and one of the leading fluorine compounds that has been recently discovered is the enantiopure trifluoromethylated molecule which is often included in biologically active compounds, chiral reagents, and in materials for optoelectronic devices.
- Subjects :
- *MOLECULES
*FLUORINE
*CHEMICAL elements
*ATOMS
*CHIRALITY
*CHEMICAL reagents
Subjects
Details
- Language :
- English
- ISSN :
- 00092665
- Volume :
- 111
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Chemical Reviews
- Publication Type :
- Academic Journal
- Accession number :
- 59576355
- Full Text :
- https://doi.org/10.1021/cr100166a