(-)-Stepholidine: a potential novel antipsychotic drug with dual D1 receptor agonist and D2 receptor antagonic actions.

Provides information on a study which examined the dual effects of (-)-Stepholidine (SPD), an active ingredient of the Chinese herb Stephania, on cortical and subcortical structures. Information on the D1 receptor agonist and D2 receptor antagonist actions of SPD; Clinical studies of SPD in schizophrenia; Conclusion.