Endobronşiyal Kitle Lezyonu Yapan Sarkoidoz.

Sarcoidosis is a multisystemic disorder with unknown etiology which affect mostly lungs and mediastinal lymph nodes. Parenchymal lung disease is common in sarcoidosis, but airways also may be affected. Endobronchial mass lesion is very rare in clinical course of the disease. A female patient with 32 age attemped with complaint of progressive cough for 1 year. Chest X-ray revealed bilateral hiler enlargement. Spirometry showed mild obstruction. There was endobronchial mass in entrance of fight lower lobe on bronchoscopy, bronchoscopic biopsy was taken. Transbronchial fine needle aspiration biopsy was taken from subearinal lymph nodes. Hystopathological examination of biopsy which was taken from endobronchial mass showed epithelioid hystiocytes and Langhan's type giant cells, non-ceseating granulomas surrounded with lymphocytes. Transbronchial biopsy revealed granulommatous inflammation. Bronchoalvolar lavage (BAL) fluid analysis showed T-lymphocyte predominance and CD4/CD8 ratio was 3,5. The patient treated with systemic corticosteroid with the diagnosis of sarcoidosis for 6 months. Endobronchial mass had dissapeared on subsequent bronchoscopy. Mediastinal lypmph nodes were smaller on control tomography. This case was presented to emphasize that sarcoidois should be taken into account in differential diagnosis of endobronchial mass lesions. [ABSTRACT FROM AUTHOR]