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One-Pot Synthesis of Salicylanilides by Direct Amide Bond Formation from Salicyclic Acid Under Microwave Irradiation.

Authors :
Lu, Cheng-Rong
Zhao, Bei
Jiang, Ying-Peng
Ding, Hao
Yang, Sheng
Source :
Synthetic Communications. 2011, Vol. 41 Issue 9, p1257-1266. 10p. 3 Diagrams, 3 Charts.
Publication Year :
2011

Abstract

[image omitted] A highly efficient protocol for the preparation of aromatic amides is described by the direct reactions between salicyclic acid and aromatic amines in the presence of phosphorous trichloride under microwave irradiation. The method has several advantages over the conventional methods, including operational simplicity, good yield, and reduced reaction time. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00397911
Volume :
41
Issue :
9
Database :
Academic Search Index
Journal :
Synthetic Communications
Publication Type :
Academic Journal
Accession number :
59754982
Full Text :
https://doi.org/10.1080/00397911.2010.481745