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Water-soluble Phenolic Compounds and Their Anti-HIV-1 Activities from the Leaves of Cyclocarya paliurus.
- Source :
-
Journal of Food & Drug Analysis . Dec2010, Vol. 18 Issue 6, p398-404. 7p. 1 Diagram, 2 Charts. - Publication Year :
- 2010
-
Abstract
- Eight phenolic compounds including five glucuronides were isolated from the leaves of Cyclocarya paliurus (Batal.) Ijinskaja, which is used as a source of tea. Their structures were characterized by spectroscopic methods. The results of biological assay showed that compounds 1 and 5 had good activities against HIV-1 induced cytopathic effects in C8166 lymphocyte at non-cytotoxic concentrations, with EC50 values of 31.74 and 10.76 uM, and therapeutic index (TI) values of >13.02 and 25.46, respectively. Relationship between molecular structures and their bioactivities was discussed. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10219498
- Volume :
- 18
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Journal of Food & Drug Analysis
- Publication Type :
- Academic Journal
- Accession number :
- 59985540