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Temperature-response polymer coating for in-tube solid-phase microextraction coupled to high-performance liquid chromatography
- Source :
-
Talanta . May2011, Vol. 84 Issue 4, p1019-1025. 7p. - Publication Year :
- 2011
-
Abstract
- Abstract: The silica nanoparticle (SiO2 NP)-deposited capillary fabricated by liquid phase deposition (LPD) was bonded by 3-(triethoxysilyl) propyl methacrylate and then modified with poly(N-isopropylacrylamide) (PNIPAAm) by polymerization. The resulting PNIPAAm modified SiO2 NP-deposited capillary was applied to in-tube solid-phase microextraction coupled to high-performance liquid chromatography (in-tube SPME–HPLC). To investigate the extraction performance of the prepared capillary, diethylstilbestrol (DES) with moderate polarity was selected as the model analyte. Results demonstrate that PNIPAAm modified SiO2 NP-deposited capillary exhibited obvious temperature responsive character. Finally, the PNIPAAm modified SiO2 NP-deposited capillary was applied to the analysis of three synthetical estrogens from milk samples. The detection limit of the method was found to be in the range 1.2–2.2ng/g, and recovery was 71.7–98.9% with relative standard deviations in the range of 2.8–12.6%. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00399140
- Volume :
- 84
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Talanta
- Publication Type :
- Academic Journal
- Accession number :
- 60379071
- Full Text :
- https://doi.org/10.1016/j.talanta.2011.03.003