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Effect of Carotid Artery Stenting on the Release of S-100B and Neurone-Specific Enolase.
- Source :
-
Angiology . Jul2011, Vol. 62 Issue 5, p376-380. 5p. - Publication Year :
- 2011
-
Abstract
- Serum levels of S-100B and neurone-specific enolase (NSE) reflect cerebral injury in a variety of neurological conditions such as stroke, traumatic brain injury, and cardiac arrest. There are limited data on the release of S-100B and NSE following carotid artery stenting (CAS). In 22 patients undergoing CAS, serial blood samples for S-100B and NSE were collected before and 2, 4, and 6 to 8 hours after the procedure. A group of 20 patients with significant CAS undergoing purely diagnostic angiography served as controls. A significant increase in S-100B levels was observed 2 hours after the procedure in patients with CAS (P = .001) with a gradual decline over the next hours. In contrast, patients who underwent purely diagnostic angiography did not show significant changes in S-100B levels up to 8 hours after the procedure. Neither patients with CAS nor those undergoing diagnostic angiography displayed any significant changes in serial NSE levels. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CAROTID artery surgery
*ANALYSIS of variance
*ANGIOGRAPHY
*BIOMARKERS
*CALCIUM-binding proteins
*CHI-squared test
*COMPUTER software
*STATISTICAL correlation
*IMMUNOASSAY
*STATISTICAL hypothesis testing
*STATISTICS
*SURGICAL stents
*T-test (Statistics)
*TIME
*DATA analysis
*THERAPEUTICS
CAROTID artery stenosis
Subjects
Details
- Language :
- English
- ISSN :
- 00033197
- Volume :
- 62
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Angiology
- Publication Type :
- Academic Journal
- Accession number :
- 60833285
- Full Text :
- https://doi.org/10.1177/0003319710387920