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Sources of cognitive exploration: Genetic variation in the prefrontal dopamine system predicts Openness/Intellect
- Source :
-
Journal of Research in Personality . Aug2011, Vol. 45 Issue 4, p364-371. 8p. - Publication Year :
- 2011
-
Abstract
- Abstract: The personality trait Openness/Intellect reflects the tendency to be imaginative, curious, perceptive, artistic, and intellectual – all characteristics that involve cognitive exploration. Little is known about the biological basis of Openness/Intellect, but the trait has been linked to cognitive functions of prefrontal cortex, and the neurotransmitter dopamine plays a key role in motivation to explore. The hypothesis that dopamine is involved in Openness/Intellect was supported by examining its association with two genes that are central components of the prefrontal dopaminergic system. In two demographically different samples (children: N =608; adults: N = 214), variation in the dopamine D4 receptor gene (DRD4) and the catechol-O-methyltransferase gene (COMT) predicted Openness/Intellect, as main effects in the child sample and as a gene-gene interaction in adults. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00926566
- Volume :
- 45
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Journal of Research in Personality
- Publication Type :
- Academic Journal
- Accession number :
- 61161795
- Full Text :
- https://doi.org/10.1016/j.jrp.2011.04.002