Back to Search
Start Over
Label-free detection of HIV-2 antibodies in serum with an ultra-high frequency acoustic wave sensor
- Source :
-
Talanta . Jul2011, Vol. 85 Issue 1, p816-819. 4p. - Publication Year :
- 2011
-
Abstract
- Abstract: Herein is described a label-free immunosensor dedicated to the detection of HIV-2. The biosensor platform is constructed as a mixed self-assembled monolayer-coated quartz wafer onto which HIV-2 immunodominant epitopes are immobilized. The biosensing properties, in terms of specific vs. non-specific antigen–antibody interactions, are evaluated with the electromagnetic piezoelectric acoustic sensor (EMPAS) using equimolar serum solutions of HIV-2 or HIV-1 monoclonal antibodies, respectively. This immunosensor constitutes the first real-world application of the EMPAS technology in the bioanalytical field. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00399140
- Volume :
- 85
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Talanta
- Publication Type :
- Academic Journal
- Accession number :
- 61172659
- Full Text :
- https://doi.org/10.1016/j.talanta.2011.04.008