Three New Sesquiterpene Pyridine Alkaloids from Euonymus fortunei.

Three new macrocyclic β-dihydroagarofuran-type sesquiterpene pyridine alkaloids, fortuneines A (), B (), and C (), together with the four known alkaloids wilfornine E (), aquifoliunine E-I (), euoverrine B (), and euojaponine I (), were isolated from the aerial parts of Euonymus fortunei. Their structures were elucidated by spectroscopic methods, including HR-ESI-MS, H- and C-NMR, DEPT, H,H-COSY, HSQC, HMBC, and ROESY. This is the first isolation of the above sesquiterpene pyridine alkaloids from this plant, except for compound . [ABSTRACT FROM AUTHOR]