The Concept of Minimal Risk: The Need for Better Guidance on the Ethics Review Process.

In this article the author discusses aspects of the report "Relative Versus Absolute Standards for Everyday Risk in Adolescent HIV Prevention Trials: Expanding the Debate," by J. Snyder, C. Miller, and G. Gray within the issue. The author notes the persuasiveness of Snyder and colleagues' argument regarding the use of a relative standard of minimal risk in HIV vaccine trials involving adolescents, and discusses Canadian regulations regarding minimal risk and ethical aspects of minimal risk.