The MTHFD1L Gene rs11754661 Marker is Not Associated with Alzheimer's Disease in a Sample of the Spanish Population.

Authors :: Ramírez-Lorca, Reposo
Boada, Mercé
Antúnez, Carmen
López-Arrieta, Jesús
Moreno-Rey, Concha
Hernández, Isabel
Marín, Juan
Gayán, Javier
González-Pérez, Antonio
Alegret, Montserrat
Tárraga, Lluis
Real, Luis M.
Ruiz, Agustín
Source :: Journal of Alzheimer's Disease. 2011, Vol. 25 Issue 1, p47-50. 4p. 1 Chart.
Publication Year :: 2011
Abstract: The MTHFD1L gene SNP variant rs11754661 was found to increase the risk of Alzheimer's disease in a recent Whole Genome Association Study [1]. We have carried out an independent study of this genetic variant in 2467 individuals from Spain. We found no evidence of association between the MTHFD1L marker and susceptibility to Alzheimer's disease in our sample. [ABSTRACT FROM AUTHOR]

Subjects :: *VITAMIN B complex
*FOLIC acid
*HOMOCYSTEINE
*POPULATION genetics
*DISEASE susceptibility
*ALZHEIMER'S disease
*GENES

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