Cloned neuropeptide Y (NPY) Y[sub1] and pancreatic polypeptide Y[sub4] receptors expressed in Chinese hamster ovary cells show considerable agonist-driven internalization, in contrast to the NPY Y[sub2] receptor.

Authors :: Parker, Steven L.
Kane, Justin K.
Parker, Michael S.
Berglund, Magnus M.
Lundell, Ingrid A.
Li, Ming D.
Source :: European Journal of Biochemistry. Feb2001, Vol. 268 Issue 4, p877. 10p. 2 Charts, 20 Graphs.
Publication Year :: 2001
Abstract: Examines the cloned neuropeptide Y and pancreatic polypeptide Y[sub 4] receptors expressed in Chinese hamster ovary cells. Association of internalized receptors with endosome-like particulates; Effect of sucrose on the internalization of receptors; Restoration of Y[sub 1] and Y[sub 4] receptors after peptide pretreatment.

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