Back to Search
Start Over
Synthesis of optically active trifluoromethyl substituted diaziridines and oxaziridines
- Source :
-
Tetrahedron . Jul2011, Vol. 67 Issue 30, p5375-5381. 7p. - Publication Year :
- 2011
-
Abstract
- Abstract: (E)-Trifluoromethyl imines were considered as ideal substrates to be transformed into the corresponding diaziridines by a direct amination reaction with nosyloxycarbamates. The diastereoselective induction was strongly controlled by the N-substituent. Similar results were obtained in the epoxidation reactions performed on the same substrates using m-CPBA as oxidant. Starting from enantiopure imines chiral diaziridines or oxaziridines were obtained with very high enantiopurity. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00404020
- Volume :
- 67
- Issue :
- 30
- Database :
- Academic Search Index
- Journal :
- Tetrahedron
- Publication Type :
- Academic Journal
- Accession number :
- 61781837
- Full Text :
- https://doi.org/10.1016/j.tet.2011.05.097