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Optimization of Microwave-Assisted Extraction of Flavonoid from Radix Astragali using Response Surface Methodology.
- Source :
-
Separation Science & Technology . 2008, Vol. 43 Issue 3, p671-681. 11p. 6 Charts, 1 Graph. - Publication Year :
- 2008
-
Abstract
- Response surface methodology (RSM) was applied to predict optimum conditions for microwave-assisted extraction (MAE) of flavonoid from Radix Astragali. A central composite design was used to monitor the effect of temperature, extraction time, solvent-to-material ratio, and the ethanol concentration on yield of total flavanoid (TFA). Optimum extraction conditions were predicted as 108.2°C, 26.7 min, 23.1 ml/g solvent-to-material ratio and 86.2% ethanol. The maximum yield 1.234±0.031 mg/g was close to the yield of Soxhlet and higher than that of ultrasound assisted extraction and heat reflux extraction. MAE was an effective alternative to conventional extraction methods. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01496395
- Volume :
- 43
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Separation Science & Technology
- Publication Type :
- Academic Journal
- Accession number :
- 61922733
- Full Text :
- https://doi.org/10.1080/01496390701812509