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Functional and Oncologic Outcomes of Bilateral Open Partial Nephrectomy Versus Bilateral Laparoscopic Partial Nephrectomy.
- Source :
-
Journal of Endourology . Jul2011, Vol. 25 Issue 7, p1193-1197. 5p. - Publication Year :
- 2011
-
Abstract
- AbstractPurpose:This study compared operative data and outcomes in patients undergoing either bilateral open partial nephrectomy (BOPN) or bilateral laparoscopic partial nephrectomy (BLPN) for synchronous bilateral kidney tumors.Patients and Methods:Patients who had undergone bilateral partial nephrectomy at our institution between 1992 and 2008 were reviewed retrospectively; 114 patients underwent either BOPN or BLPN. Ischemia time, tumor size, and renal function outcomes immediately after each surgery, at an intermediate time point (≤12 months), and at a late time point (>12 months) were compared. Oncologic outcomes were also evaluated using Kaplan-Meier analysis.Results:BOPN and BLPN were conducted in 92 and 22 patients, respectively. Average tumor size was larger in the BOPN group (4.1 vs2.7 cm; P=0.001); however, pathologic stage was equivalent (P=0.52). Hospital stay was longer in the BOPN group (5.6 vs4.0 d; P<0.001). Preoperative estimated glomerular filtration rates (eGFR) in the BOPN and BLPN groups were both ≥60 mL/min/1.73m2. Percent decrease in eGFR between the two groups was 38% in the BLPN group and 27% in the BOPN group (P=0.03). Cancer-specific and recurrence-free survival rates were equivalent between groups over a mean follow-up of 5.5 years.Conclusions:BOPN and BLPN resulted in equivalent intermediate-term oncologic control. BLPN was associated with a larger percent decrease in eGFR. As ischemia times shorten for contemporary laparoscopic partial nephrectomies, it is expected that functional outcomes will be equivalent. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08927790
- Volume :
- 25
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Journal of Endourology
- Publication Type :
- Academic Journal
- Accession number :
- 62652929
- Full Text :
- https://doi.org/10.1089/end.2010.0519