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Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long...

Authors :
Christensen, Julie L.
Weissman, Irving L.
Source :
Proceedings of the National Academy of Sciences of the United States of America. 12/4/2001, Vol. 98 Issue 25, p14541. 6p. 3 Color Photographs, 3 Charts, 29 Graphs.
Publication Year :
2001

Abstract

Analyzes the functional differences in cells of hematopoietic stem cell (HSC) phenotype that do or do not express the receptor tyrosine kinase Flk-2. Heterogenous expression of Flk-2 on the HSC population; Definition by the receptor tyrosine kinases of a pathway of HSC differentiation; Long-term reconstitution ability of Flk-2[sup +] mouse fetal liver HSCs.

Details

Language :
English
ISSN :
00278424
Volume :
98
Issue :
25
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
6412803
Full Text :
https://doi.org/10.1073/pnas.261562798