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High incidence of IDH mutations in acute myeloid leukaemia with cuplike nuclei.

Authors :
Rakheja, Dinesh
Konoplev, Sergej
Su, Mu
Wheeler, David
Muzny, Donna M.
Ruvolo, Vivian R.
Collins, Robert
Karandikar, Nitin J.
Andreeff, Michael
Medeiros, Leonard Jeffrey
Chen, Weina
Source :
British Journal of Haematology. Oct2011, Vol. 155 Issue 1, p125-128. 3p. 1 Color Photograph, 1 Chart.
Publication Year :
2011

Abstract

The article focuses on the study of Dinesh Rakheja and colleagues related to the incidence of isocitrate dehydrogenase (IDH) mutations in acute myeloid leukemia (AML) with cuplike nuclei. It mentions that the study is undertaken through a review of Wright-Giemsa-stained peripheral blood, hematoxylin-eosin-stained bone marrow dot, and bone marrow aspirate smears. The results of the study show that IDH mutations is associated with outcome in AML patients.

Details

Language :
English
ISSN :
00071048
Volume :
155
Issue :
1
Database :
Academic Search Index
Journal :
British Journal of Haematology
Publication Type :
Academic Journal
Accession number :
65246700
Full Text :
https://doi.org/10.1111/j.1365-2141.2011.08646.x