Hairpin versus Extended DNA Binding of a Substituted Β-Alanine Linked Polyamide.

Authors :: Woods, Craig R.
Ishii, Takahiro
Bing Wu
Bair, Kenneth W.
Boger, Dale L.
Source :: Journal of the American Chemical Society. 3/13/2002, Vol. 124 Issue 10, p2148. 5p. 2 Color Photographs, 4 Diagrams, 5 Charts, 1 Graph.
Publication Year :: 2002
Abstract: Examines the synthesis of pyrrole polyamides using a central beta-alanine subunit. Effect of central beta-alanine linker on DNA binding; Distinction between hairpin and extended DNA binding of beta-alanine linked polyamides; Use of fluorescent intercalator displacement in determining DNA binding properties.

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