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Non-sedating antihistamine drugs and cardiac arrhythmias - biased risk estimates from spontaneous reporting systems?

Authors :
De Bruin, M.L.
van Puijenbroek, E.P.
Egberts, A.C.G.
Hoes, A.W.
Leufkens, H.G.M.
Source :
British Journal of Clinical Pharmacology. Apr2002, Vol. 53 Issue 4, p370-374. 5p.
Publication Year :
2002

Abstract

Discusses the use of spontaneous reports of adverse events to estimate the risk for developing cardiac arrhythmias due to the systemic use of nonsedating antihistamine drugs in the Netherlands. Risk estimate before and after the regulatory action to recall the over-the-counter status of some of these drugs; Indication that nonsedating antihistamines might have an increased risk for inducing arrhythmias.

Details

Language :
English
ISSN :
03065251
Volume :
53
Issue :
4
Database :
Academic Search Index
Journal :
British Journal of Clinical Pharmacology
Publication Type :
Academic Journal
Accession number :
6662604
Full Text :
https://doi.org/10.1046/j.1365-2125.2002.01569.x