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Emergence of 2009A/H1N1 cases in a tertiary care hospital in New Delhi, India.
- Source :
-
Influenza & Other Respiratory Viruses . Nov2011, Vol. 5 Issue 6, pe552-e557. 6p. - Publication Year :
- 2011
-
Abstract
- Please cite this paper as: Broor et al. (2011) Emergence of 2009A/H1N1 cases in a tertiary care hospital in New Delhi, India. Influenza and Other Respiratory Viruses 5(6), e552-e557. Objective To determine virologic and epidemiologic characteristics of pandemic (H1N1) 2009 at All India Institute of Medical Sciences (AIIMS) a tertiary care hospital in New Delhi, India. Methods Nasal and throat swabs from patients with febrile acute respiratory illness (FARI) from August to December 2009 ( n = 1401) were tested for 2009A/H1N1 and seasonal influenza A viruses by real-time RT-PCR. Results Of 1401 samples tested, 475 (33·9%) were positive for influenza A, of these majority (412; 87%) were 2009A/H1N1, whereas the remaining 63 (13%) were seasonal influenza A (49 were A/H3 and 14 were A/H1). While co-circulation of 2009A/H1N1 and A/H3 was observed in August-September, subsequent months had exclusive pandemic influenza activity (October-December 2009). Pandemic 2009A/H1N1 emergence did not follow typical seasonal influenza seasonality in New Delhi, which normally peaks in July-August, but instead showed bimodal peaks in weeks 39 and 48 in 2009. The percent of specimens testing positive for 2009A/H1N1 influenza virus was found to be highest in >5- to 18-year age group (41·2%; OR = 2·3; CI = 1·6-3·2; P = 0·00). Conclusions Taken together, our data provide high prevalence of pandemic 2009A/H1N1 in urban New Delhi with bimodal peaks in weeks 39 and 48 and highest risk group being the children of school-going age (aged >5-18). [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17502640
- Volume :
- 5
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Influenza & Other Respiratory Viruses
- Publication Type :
- Academic Journal
- Accession number :
- 66644520
- Full Text :
- https://doi.org/10.1111/j.1750-2659.2011.00274.x