NHC triggered cascade metal-free synthesis of 2,3-diarylated indoles under solvent-free conditions

Authors :: Yao, Changsheng
Wang, Donglin
Lu, Jun
Qin, Bingbin
Zhang, Honghong
Li, Tuanjie
Yu, Chenxia
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Nov2011, Vol. 52 Issue 46, p6162-6165. 4p.
Publication Year :: 2011
Abstract: Abstract: A new cascade strategy to the synthesis of 2,3-diarylated indoles via the metal-free reaction of aryl aldehyde and aryl amine triggered by N-heterocyclic carbene (NHC) under solvent-free conditions, has been disclosed. The protocol has the advantages of easy work-up, high yields, wide application scope, and an environmentally benign procedure compared with the reported methods. [Copyright &y& Elsevier]

Subjects :: *ORGANIC synthesis
*INDOLE
*ORGANIC solvents
*ALDEHYDES
*HETEROCYCLIC compounds
*AMINES
*CHEMICAL reactions

Language :: English
ISSN :: 00404039
Volume :: 52
Issue :: 46
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 66661597
Full Text :: https://doi.org/10.1016/j.tetlet.2011.09.041

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