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Mechanized Silica Nanoparticles: A New Frontier in Theranostic Nanomedicine.

Authors :
Michael W. Ambrogio
Courtney R. Thomas
Yan-Li Zhao
Jeffrey I. Zink
J. Fraser Stoddart
Source :
Accounts of Chemical Research. Oct2011, Vol. 44 Issue 10, p903-913. 11p.
Publication Year :
2011

Abstract

Medicine can benefit significantly from advances in nanotechnology because nanoscale assemblies promise to improve on previously established therapeutic and diagnostic regimes. Over the past decade, the use of delivery platforms has attracted attention as researchers shift their focus toward new ways to deliver therapeutic and/or diagnostic agents and away from the development of new drug candidates. Metaphorically, the use of delivery platforms in medicine can be viewed as the “bow-and-arrow” approach, where the drugs are the arrows and the delivery vehicles are the bows. Even if one possesses the best arrows that money can buy, they will not be useful if one does not have the appropriate bow to deliver the arrows to their intended location. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00014842
Volume :
44
Issue :
10
Database :
Academic Search Index
Journal :
Accounts of Chemical Research
Publication Type :
Academic Journal
Accession number :
66716873
Full Text :
https://doi.org/10.1021/ar200018x