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Total Synthesis of Bryostatin 7 via C-C Bond-Forming Hydrogenation.

Authors :
Yu Lu
Sang Kook Woo
Krische, Michael J.
Source :
Journal of the American Chemical Society. 9/7/2011, Vol. 133 Issue 35, p13876-13879. 4p.
Publication Year :
2011

Abstract

The marine macrolide bryostatin 7 is prepared in 20 steps (longest linear sequence) and 36 total steps with five C—C bonds formed using hydrogenative methods. This approach represents the most concise synthesis of any bryostatin reported, to date. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00027863
Volume :
133
Issue :
35
Database :
Academic Search Index
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
66777651
Full Text :
https://doi.org/10.1021/ja205673e